AptamerSELEX

由 Q Liu 著作 · 2020 · 被引用 36 次 — Aptamers, single-stranded DNAs or RNAs, can be selected from a library containing random sequences using a method called Systematic ...

由 N Lin 著作 · 2021 · 被引用 23 次 — Using cell-SELEX, we generated and characterized an aptamer, termed S6-1b, that can distinguish the molecular differences between glioma cell ...

由 C Narayan 著作 · 2022 · 被引用 5 次 — Since its inception in the early 1990s, SELEX remains the gold standard for discovering RNA aptamers specific for proteins and small ...

由 S Saito 著作 · 2021 · 被引用 39 次 — In the SELEX procedure, one of the keys for the effective acquisition of high-affinity and functional aptamer sequences is the separation stage ...

Aptamers with affinity for a desired target are selected from a large oligonucleotide library through a process called SELEX, which stands for Sequential ...

2017年8月2日 — 為提高SELEX的成功率，縮短篩選週期、賦予核酸適體特定功能，目前已有數十種改進的SELEX技術被建立，並成功篩選到數千個具有應用價值的核酸適體，靶點應用 ...

由 M Kohlberger 著作 · 2022 · 被引用 96 次 — In microarray‐based SELEX, aptamers are coupled to a microwell plate through chemical linkage, and the fluorescently labeled target molecule is added in ...

由 Z Zhuo 著作 · 2017 · 被引用 333 次 — Aptamers are short DNA/RNA oligonucleotides capable of binding to target molecules with high affinity and specificity.

由 M Blind 著作 · 2015 · 被引用 346 次 — The protocol for the in vitro selection of aptamers, SELEX, was developed in the year 1990 (refs.,) and demonstrated the capacity of aptamers to bind a wide ...